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How the Retina Works

Understanding Retinal Conditions and Your Vision

Common Retinal Conditions

Retinal disease takes many forms, and each type affects the eye in a different way. Some develop gradually over years, while others appear suddenly and require immediate attention.

Age-related macular degeneration (AMD) is one of the most common causes of vision loss in adults over 50. It comes in two forms that require different approaches to treatment.

Dry AMD involves gradual thinning of the macula and is the more common form. It can progress to geographic atrophy, a condition where patches of retinal cells are permanently lost. Wet AMD is less common but more aggressive. It develops when abnormal blood vessels grow beneath the retina and leak fluid or blood, causing faster damage.

Diabetic retinopathy (DR) occurs when high blood sugar damages the tiny blood vessels in the retina. Over time, these vessels may swell, leak, or grow abnormally. Diabetic macular edema (DME) is a related condition in which fluid builds up in the macula, blurring central vision. Both conditions are leading causes of vision loss in working-age adults, though outcomes have improved with better screening and treatment.

A retinal vein occlusion (RVO) happens when a vein carrying blood away from the retina becomes blocked. The blockage causes fluid to build up in the macula, leading to swelling and vision loss. Risk factors include high blood pressure, diabetes, and elevated eye pressure.

A retinal tear happens when the vitreous gel inside the eye pulls on the retina and creates a break in its surface. If fluid passes through the tear and lifts the retina away from the tissue beneath it, a retinal detachment occurs. This is a medical emergency. Without prompt treatment, a detached retina can cause permanent vision loss. People with high myopia (severe nearsightedness), a history of eye surgery, or a family history of detachment are at increased risk.

Several additional conditions affect the macula and vitreous. A macular hole is a small break in the center of the macula that distorts or blurs central vision. An epiretinal membrane (also called a macular pucker) is a thin layer of scar tissue that forms over the macula and causes wrinkling or distortion. A posterior vitreous detachment (PVD) occurs when the vitreous gel separates from the retina, often causing floaters and flashes of light.

Who Is at Risk

Retinal disease can affect anyone, but certain factors raise the likelihood of developing these conditions. Knowing your risk can help you and your retina specialist decide how often you need to be monitored.

Age is the most significant risk factor for several retinal conditions, particularly AMD. The likelihood of developing AMD increases steadily after age 50 and rises sharply with each decade of life. Regular screenings become increasingly important as you get older.

Diabetes is the primary risk factor for diabetic retinopathy and DME. High blood sugar damages the small blood vessels of the retina over time, often before any symptoms are noticed. High blood pressure and cardiovascular disease also raise the risk of retinal vein occlusion.

Cigarette smoking is a well-established risk factor for AMD. It accelerates damage to the retina and can worsen the course of the disease. Quitting smoking at any age can help reduce this risk. A diet rich in leafy green vegetables and fish, along with UV-protective sunglasses, may also support long-term retinal health.

A family history of AMD, retinal detachment, or inherited retinal disease increases your personal risk. If a close relative has been diagnosed with a retinal condition, it is important to share that history with your eye care provider. Some inherited retinal diseases, such as retinitis pigmentosa, are caused by specific gene mutations and may be detected early with genetic testing.

High myopia, or severe nearsightedness, stretches and thins the retina, making it more vulnerable to tears and detachment. Prior eye surgery and certain medications or systemic health conditions may also influence retinal health. Your retina specialist will review all relevant factors when assessing your risk.

Signs and Symptoms to Know

Retinal conditions can develop silently, but they often produce warning signs that should not be ignored. Recognizing these symptoms early can make a meaningful difference in treatment outcomes.

Many retinal conditions affect the macula first. You may notice that reading, recognizing faces, or seeing fine detail has become harder. Straight lines may look wavy or bent, a symptom sometimes called metamorphopsia.

Floaters are small spots, threads, or cobweb-like shapes that drift across your field of vision. An occasional floater is usually harmless. However, a sudden increase in floaters, especially when accompanied by flashes of light, can be a sign of a retinal tear or detachment and requires immediate evaluation.

Some conditions, including retinitis pigmentosa, gradually reduce peripheral (side) vision before affecting central sight. Difficulty seeing in dim lighting or at night is often an early sign. These symptoms can progress slowly, so they may not be noticed right away.

A sudden loss of vision in one eye, or the appearance of a curtain or shadow across part of your visual field, is a medical emergency. Do not wait for a scheduled appointment. See a retina specialist or go to an emergency room right away, as prompt treatment can be the difference between saving and losing vision.

How Retinal Disease Is Diagnosed

A thorough evaluation allows your retina specialist to identify the type and severity of a retinal condition. Several complementary tests are often used together to get a complete picture of your retinal health.

A dilated eye exam is the foundation of any retinal evaluation. Eye drops widen the pupil so your retina specialist can see the retina, macula, and optic nerve clearly. This exam can reveal signs of AMD, diabetic retinopathy, and retinal tears, often before you notice any symptoms yourself.

Optical coherence tomography (OCT) is a painless, non-invasive imaging test that produces detailed cross-sectional images of the retina. It allows your retina specialist to measure retinal thickness and detect fluid, swelling, or structural changes with great precision. OCT angiography (OCT-A) can also map the retinal blood vessels without the use of injectable dye.

Fluorescein angiography involves injecting a dye into a vein in the arm and then photographing the retina as the dye travels through its blood vessels. This test identifies areas of leakage or abnormal vessel growth. Indocyanine green (ICG) angiography uses a different dye to visualize the deeper choroidal vessels beneath the retina.

Wide-field imaging captures a broad view of the retina and can reveal disease in areas that standard photography may miss. Fundus autofluorescence highlights areas of RPE damage and is particularly useful in monitoring geographic atrophy. B-scan ultrasound uses sound waves to image the interior of the eye and is helpful when the retina cannot be seen directly due to bleeding or clouding.

Treatment Options for Retinal Disease

Treatment depends on the type and stage of retinal disease. Our team of vitreoretinal fellowship-trained, board-certified retina specialists offers a full range of medical, laser, and surgical treatments tailored to each patient's needs.

Anti-VEGF therapy is the most widely used treatment for wet AMD, DME, retinal vein occlusion, and diabetic retinopathy. These medications block vascular endothelial growth factor (VEGF), a protein that drives abnormal blood vessel growth and leakage in the retina. They are delivered as intravitreal injections, meaning they are injected directly into the vitreous cavity of the eye in a brief, well-tolerated office procedure.

Anti-VEGF agents used in retinal care include:

  • Eylea (aflibercept): commonly given every 4 to 8 weeks after an initial loading phase
  • Lucentis (ranibizumab): one of the first anti-VEGF medications approved for eye conditions
  • Avastin (bevacizumab): used off-label for retinal conditions and widely studied
  • Vabysmo (faricimab): a bispecific antibody that targets both VEGF and Ang-2, with dosing intervals of up to 16 weeks in eligible patients

Your retina specialist will recommend the medication and dosing schedule that best fits your condition and overall health.

Geographic atrophy is an advanced form of dry AMD in which patches of retinal cells are permanently lost. It is treated differently from wet AMD. Izervay (avacincaptad pegol), a complement inhibitor given monthly by injection, has been approved to slow the progression of geographic atrophy. Iluvien (fluocinolone acetonide implant) is a sustained-release steroid implant used for DME and certain retinal conditions when other treatments are insufficient. These treatments do not restore vision that has already been lost but can help slow further decline.

Laser photocoagulation uses a focused beam of light to seal leaking blood vessels, treat abnormal retinal tissue, or close retinal tears before they progress to detachment. It is used for diabetic retinopathy, retinal tears, and certain retinal vein occlusions. Panretinal photocoagulation (PRP) treats a wider area of the retina in cases of advanced proliferative diabetic retinopathy. Laser treatment helps prevent further vision loss rather than restore vision that has already been affected.

Some retinal conditions require surgery. Pars plana vitrectomy involves removing the vitreous gel from inside the eye and repairing the retina directly. It is used to treat retinal detachment, macular holes, and epiretinal membranes. Scleral buckling places a flexible silicone band around the outside of the eye to push the wall inward and support a detached retina. Pneumatic retinopexy uses a gas bubble injected into the eye to press the retina back into place, often combined with laser or cryotherapy (freezing treatment). Your retina specialist will recommend the most appropriate surgical approach based on the specifics of your condition.

What to Expect During Treatment

Knowing what is involved in common retinal procedures can help ease any anxiety before your appointment. Most treatments are performed in the office or as outpatient procedures, with minimal downtime.

The eye is numbed with drops or a small amount of anesthetic before the injection, so most patients feel only mild pressure or brief discomfort. The injection itself takes just a few seconds. You may notice some floaters afterward as the medication disperses. Most patients return to their normal activities the same day.

Retinal surgeries are typically performed on an outpatient basis under local or general anesthesia. Recovery time varies depending on the type of surgery performed. If a gas bubble is placed inside the eye during vitrectomy or pneumatic retinopexy, you may need to maintain a specific head position for several days to keep the bubble properly positioned against the retina. Your retina specialist will give you detailed post-operative instructions.

Many retinal conditions require long-term management rather than a single course of treatment. Regular follow-up visits with repeat OCT imaging allow your retina specialist to track how your retina is responding and adjust the treatment plan when needed. Staying consistent with follow-up appointments is one of the most important things you can do to protect your vision over time.

Living Well with a Retinal Condition

A retinal diagnosis can feel overwhelming, but many people continue to live full and active lives with the right support and habits. Small changes can make a real difference in protecting the vision you have.

Vision changes from retinal conditions can affect reading, driving, cooking, and other daily tasks. Low vision aids, including magnifying devices and adjusted lighting, can help with many activities. A low vision rehabilitation specialist can work with you to find tools and strategies suited to your specific needs.

Keeping underlying conditions such as diabetes and high blood pressure well controlled can slow the progression of related retinal diseases. Wearing UV-protective sunglasses, eating a diet rich in leafy greens and colorful vegetables, and not smoking all support long-term retinal health. The AREDS2 formula, a specific combination of vitamins and minerals, has been shown to reduce the risk of progression in intermediate and advanced AMD.

Anxiety, frustration, and sadness are normal responses to a retinal diagnosis, especially when vision is affected. Talking with your care team about your concerns is always encouraged. Patient advocacy organizations and support groups exist specifically for people living with macular degeneration, diabetic eye disease, and inherited retinal conditions, and many patients find them genuinely helpful.

When to See a Retina Specialist

Knowing when to seek care can protect your vision and in some cases prevent permanent damage. Some situations call for immediate attention, while others are best addressed through planned screening and referral.

Certain symptoms should never be ignored or left until the next available appointment. Go to a retina specialist or an emergency room immediately if you experience any of the following:

  • A sudden increase in floaters
  • New flashes of light in your vision
  • A shadow, curtain, or dark area across part of your visual field
  • Sudden vision loss in one eye

These symptoms can indicate a retinal tear or detachment, both of which require urgent treatment to prevent permanent vision loss.

Even without symptoms, regular dilated eye exams are important for detecting retinal disease before it causes noticeable vision changes. Adults over 50 should follow the exam schedule recommended by their eye care provider. People with diabetes should have a dilated retinal exam at least once a year, as diabetic retinopathy often has no symptoms in its early stages.

Your primary eye care provider, whether an optometrist or a general ophthalmologist, can refer you to a retina specialist if a retinal condition is suspected. You do not need to wait for a problem to become severe before seeking a referral. Earlier evaluation almost always leads to better outcomes.

Frequently Asked Questions

These answers address common questions that go beyond what is covered in the sections above, including guidance on next steps and practical decision-making.

An ophthalmologist is a medical doctor who diagnoses and treats eye diseases. A retina specialist is an ophthalmologist who has completed an additional one to two years of fellowship training specifically focused on diseases and surgery of the retina, vitreous, and macula. This extra training equips retina specialists to manage complex conditions such as retinal detachment, macular degeneration, and diabetic retinopathy using advanced surgical and medical techniques that go beyond the scope of general eye care.

Yes, and this is one of the most important reasons for regular screening. Conditions like early AMD and diabetic retinopathy can cause significant structural damage to the retina before any change in vision is noticeable. By the time symptoms appear, the disease may already be at an advanced stage. A dilated exam or OCT imaging can reveal these changes early, when treatment is most effective.

Intravitreal injections are among the most commonly performed medical procedures performed today, and serious complications such as infection are rare. The eye is thoroughly numbed before each injection, and most patients report only a brief sensation of pressure rather than pain. If you feel anxious about injections, letting your retina specialist know ahead of time allows them to take extra steps to keep you comfortable throughout the procedure.

The answer depends on the condition, how much damage has already occurred, and how quickly treatment begins. Some patients do experience meaningful vision improvement, particularly with anti-VEGF therapy for wet AMD or DME when started early. For others, the primary goal is to stabilize vision and prevent further loss. This is why early detection matters so much. The sooner treatment begins, the more vision there is to protect.

Treatment frequency varies by condition and how well the retina responds. Anti-VEGF injections are often given as frequently as every 4 weeks early in treatment, with intervals sometimes extended as the condition stabilizes. Laser procedures are typically not repeated as often. Your retina specialist will use imaging at each visit to guide these decisions, and your schedule may change over time as your treatment progresses.

The AREDS2 formula has strong evidence supporting its use in patients with intermediate AMD or advanced AMD in one eye, where it has been shown to reduce the risk of progression to advanced stages. It is not recommended for people with early AMD or no AMD. If you have been diagnosed with macular disease, ask your retina specialist whether a supplement is appropriate for your specific stage and situation, as not everyone benefits equally.

Schedule a Visit with Atlantic Retina Center

Atlantic Retina Center is a single-specialty vitreoretinal practice serving patients throughout the Eastern Shore of Maryland and Delaware. Our team of fellowship-trained, board-certified retina specialists is dedicated exclusively to the diagnosis and treatment of retinal, vitreous, and macular disease. Whether you are experiencing new symptoms, managing an existing condition, or seeking a second opinion, we are here to provide expert care focused entirely on protecting your vision.

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    Dover, Delaware

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    Easton, Maryland

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    Milford, Delaware

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    Dover, Delaware

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    Dover, Delaware

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    Easton, Maryland

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    Salisbury, Maryland

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    Salisbury, Maryland

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    Milford, Delaware

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    Salisbury, Maryland

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    Salisbury, Maryland

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    Milford, Delaware

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    K R

    Dover, Delaware

  • “Dr. Lagonigro was patient and understanding. His office staff professional, courteous and very helpful.”

    John Moschitta

    Dover, Delaware

  • “We went to Azar Eye Institute for an emergency due to my husband’s sudden floaters. They were prompt, caring, and fit us in immediately. Grateful for their excellent, attentive care!”

    Kirsten Krogen

    Ocean Pines, Maryland

  • “Dr. Paul is passionate about patient care, listens closely, and always puts patients first. I travel to see him; he and his team provide unbelievable service and support!”

    Kathleen Calvert

    Easton, Maryland

  • “I visited Atlantic Retina Center for macular degeneration. Dr. Schwartz and staff were professional and skilled, with excellent equipment and care. Highly recommend their services.”

    Chaz Farkass

    Easton, Maryland

  • “Doctor Paul and the entire staff were absolutely over the top with concern and care. We need more doctors in any branch of medical care to take lessons from the Staff and Doctor Paul!”

    Vernon Spear

    Easton, Maryland

  • “Everyone is very pleasant. The Dr. gave me good news!”

    Bill Schaefer

    Dover, Delaware

  • “Dr Schwartz and his team provide first rate care. I have wet AMD in both eyes and I depend on these folks to protect my eyesight -- and they do!!”

    Len Smith

    Salisbury, Maryland

  • “My wife had retinal detachment. Dr. did initial evaluation, Dr. performed surgery, skills impeccable, thorough and considerate. Staff top notch. Grateful!”

    Rich Durbin

    Milford, Delaware

  • “If it weren’t for Dr. Schwartz and his staff, I would’ve lost my most precious gift. Thank you a billion times over for your incredible care!”

    Darrell

    Easton, Maryland

  • “Dr. Schwartz and his staff are friendly, professional, and efficient. Highly recommend for excellent eye care.”

    Melanie Dement

    Easton, Maryland

  • “It may have taken a little but worth the wait. Beautiful office, friendly efficient staff. ”

    Linda Foskey

    Milford, Delaware

  • “Dr. Paul Lagonigro and staff gave me confidence and kept me informed. Forever grateful to Dr. Joseph Schwartz who performed my surgery and the entire Atlantic Retina Center team for excellent care.”

    J.D

    Salisbury, Maryland

  • “I was scared about my eye injury, but they explained everything and helped me not worry.”

    J M

    Dover, Delaware

  • “Well organized office. Great staff. First visit involved emergency repair of torn retina by Dr. Schwartz for which I was very appreciative. He and the staff continue with follow up care. Many thanks.”

    Diane Malone

    Salisbury, Maryland

  • “Thank you. We had an exceptional experience and our concerns were addressed with compassion and understanding.”

    Mar Ker

    Dover, Delaware

  • “The staff is always friendly and knowledgeable. My doctor is thorough in her diagnosis, providing professional and attentive eye care. Highly recommend!”

    J 5

    Ocean Pines, Maryland

  • “I’m an orthopedic surgeon—often on the emergency side. This time, Dr. Paul Lagonigro cared for my mother in an eye crisis. His team was professional, the gear was state‑of‑the‑art; thank you!”

    William Doran

    Salisbury, Maryland

  • “Great personal patient attention. Very organized. They handled everything for my cataract surgery and follow-up appointments were informative. Great staff.”

    Lisa Calvert

    Milford, Delaware

  • “Dr. Paul is the best. The office is responsive and the care is the reason for my eyesight being the best it can be.”

    Susan Watkins

    Salisbury, Maryland

  • “Friendly staff. Dr. Schwartz explains things very well. Very clean facility.”

    Ray T

    Dover, Delaware

  • “Everyone professional, took time to explain. Nicole did a great job and was patient helping me understand. I really appreciate the overall experience.”

    Rowland Gaunt

    Milford, Delaware

Ready to protect your vision